In order to investigate the effects of neem oil, prime plus solution and fatty alcohol on tobacco suckers control. After topping activities in different treatments, an experiment was done in research centre of Tirtash in 2009-2010. This experiment was conducted on Randomized Complete Block Design with three replications. Treatments included neem oil in the amounts of zero, five, 10, 15, 20, 25 and 30 litres per hectare, prime plus solution in the amounts of four litres per hectare, fatty alcohol solution in the amounts of 18 litres per hectare and manual control treatment. The results indicated that the differences between treatments on the leaf length, leaf width and the amount of chlorophyll of the leaves after topping were significant. Treatments of fatty alcohol and prime plus respectively have the most length and the most width of the leaves and the prim plus solution had the most amounts of chlorophyll. The treatments, considering the percentage of the ranks of tobacco, had meaningful differences of one percent to each other. The most percentage of rank one belonged to the manual control treatment rank two belonged to the treatment of fatty alcohol and rank three belonged to the treatment of not using of neem oil. Considering the price of one kilo of tobacco, the differences between different treatments were not meaningful. And according to the quality properties, no significant differences were seen among the treatments. Heading lateral buds have the most impact on the yield of tobacco leaf and in other words on the quantitative properties of tobacco.